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Publikatsioonid

2021 Publikatsioonid


Farmatseutiline tehnoloogia, Nanotehnoloogia & Füüsikaline farmaatsia

Diltemiz, S.E.; Tavafoghi, M.; de Barros, N.R.; Kanada, M.; Heinämäki, J.; Contag, C.; Seidlits, S.; Ashammakhi, N. (2021). Use of artificial cells as drug carriers (review article). Materials Chemistry Frontiers, 1-22; DOI: 10.1039/d1qm00717c

Anderspuk, H.; Viidik, L.; Olado, K.; Kogermann, K.; Juppo, A.; Heinämäki, J.; Laidmäe, I. (2021). Effects of crosslinking on the physical solid-state and dissolution properties of 3D-printed theophylline tablets. Annals of 3D Printed Medicine, 4 100031, 1-8; https://doi.org/10.1016/j.stlm.2021.100031

Viidik, L.; Vesala, J.; Laitinen, R.; Korhonen, O.; Ketolainen, J.; Aruväli, J.; Kirsimäe, K.; Kogermann, K.; Heinämäki, J.; Laidmäe, I.; Ervasti, T. (2021). Preparation and characterization of hot-melt extruded polycaprolactone-based filaments intended for 3D-printing of tablets. European Journal of Pharmaceutical Sciences, 158, 105619, 1-8; DOI: 10.1016/j.ejps.2020.105619

Laidmäe, I.; Meos, A.; Alainezhad Kjærvik, I.; Ingebrigtsen, S.G.; Škalko-Basnet, N.; Kirsimäe, K.; Romann, T.; Joost, U.; Kisand, V.; Kogermann, K. (2021). Electrospun amphiphilic nanofibers as templates for in situ preparation of chloramphenicol-loaded liposomes. Pharmaceutics, 13, 1742, 1-22; https://doi.org/10.3390/pharmaceutics13111742

Ramos, C.; Lanno G.-M.; Laidmäe, I.; Meos, A.; Härmas R.; Kogermann, K. (2021). High humidity electrospinning of porous fibers for tuning the release of drug delivery systems. International Journal of Polymeric Materials and Polymeric Biomaterials, 70, 12, 880-892; https://doi.org/10.1080/00914037.2020.1765361

Tedersoo, L.; Küngas, R.; Oras, E.; Köster, K.; Eenmaa, H.; Leijen, Ä.; Pedaste, M.; Raju, M.; Astapova, A.; Lukner, H.; Kogermann, K.; Sepp, T. (2021). Data sharing practices and data availability upon request differ across scientific disciplines. Scientific Data 8, 192, 1-11;  https://doi.org/10.1038/s41597-021-00981-0

Kangro, K.; Kurašin, M.; Gildemann, K.; Sankovski, E.; Žusinaite, E.; Sandra Lello, L.; Pert, R.; Kavak, A.; Poikalainen, V.; Lepasalu, L.; Kuusk, M.; Pau, R.; Piiskop, S.; Rom, S.; Oltjer, R.; Tiirik, K.; Kogermann, K.; Plaas, M.; Tiirats, T.; Aasmäe, B.; Plaas, M.; Krinka, D.; Talpsep, E.; Kadaja, M.; Gerhold, J.M.; Planken, A.; Tover, A.; Merits, A.; Männik, A.; Ustav Jr, M.; Ustav, M. (2021). Bovine colostrum derived antibodies against SARS-CoV-2 show great potential to serve as a prophylactic agent. MedRxiv, 1-20; https://doi.org/10.1101/2021.06.08.21258069

Duong, T.T.; Isomäki, A.; Paaver, U.; Laidmäe, I.; Tõnisoo, A.; Hai Yen, T.T., Kogermann, K.; Raal, A.; Heinämäki, J.; Hue Pham, T.-M. (2021). Nanoformulation and evaluation of oral berberine-loaded liposomes. Molecules 26, 2591, 1-18; https://doi.org/10.3390/molecules26092591

De la Paz, N.; Fernández, M.; López, O.; Garcia, C.; Nogueira, A.; Torres, L.; Turiño, W.; Heinämäki, J. (2021). Spray drying of chitosan acid salts: process development, scaling up and physicochemical material characterization. Marine Drugs 19, 329, 1-16; https://doi.org/10.3390/
md19060329

De Sio, L.; Ding, B.; Focsan, M.; Kogermann, K.; Pascoal-Faria, P.; Petronela, F.; Mitchell, G.; Zussman, E.; Pierini, F. (2021). Personalized reusable face masks with smart nano-assisted destruction of pathogens for COVID-19: A visionary road. Chemistry – A European Journal 27, 6112-6130; doi.org/10.1002/chem.202004875

Farmakognoosia & Farmatseutiline bioloogia

Nguyen, Khan Viet; Nguyen, Thu Oanh; Ho, Duc Viet; Heinämäki, Jyrki; Raal, Ain; Nguyen, Hoai Thi (2021). In vitro acetylcholinesterase inhibitory and antioxidant activity of Alphonsea tonkinensis A.DC. Natural Product Communications 16 (9), 1-5; DOI: 10.1177/1934578X211042134

Nguyen, Khan Viet; Ho, Duc Viet; Le, Anh Tuan; Heinämäki, Jyrki; Raal, Ain; Nguyen, Hoai Thi (2021). Secondary metabolites from Alphonsea tonkinensis A.DC. showing inhibition of nitric oxide production and cytotoxic activity.  Journal of Pharmacy & Pharmacognosy Research, 9, 1, 24-32; http://jppres.com/jppres

Nguyen, Quoc Binh; Nguyen, Thanh Tung; Nguyen, Phuong Hanh; Luu, Hong Truong; Nguyen, Hieu Cuong; Kieu, Thi Hoai; Nguyen, Viet Than; Raal, Ain (2021). Chemical composition of essential oils from the leaves, stems and roots of Aristolochia petelotii O.C. Schmidt growing in Vietnam. Journal of Essential Oil Bearing Plants, 24, 1-8; DOI: 10.1080/0972060X.2021.1987335

Nguyen, Thanh Tung; Nguyen, Viet Than; Nguyen, Quang Hung; Raal, Ain (2021). The chemical investigation of four Balanophora species and cytotoxicity with Inhibition of NO production. International Journal of Pharmaceutical Research & Allied Sciences, 10, 2, 1-9; https://doi.org/10.51847/rR1GviyLsl

Koshovyi, O.; Raal, A.; Kireyev, I.; Tryshchuk, N.; Ilina, T.; Romanenko, Y.; Kovalenko, S.M.; Bunyatyan, N. (2021). Phytochemical and psychotropic research of motherwort (Leonurus cardiaca L.) modified dry extracts. Plants 10, 230, 1-17; https://doi.org/10.3390/plants10020230

Doan, T.Q.; Ho, D.V.; Le, N.T.; Le, A.T.; Phan, K.V.; Nguyen, H.T.; Raal, A. (2021). Chemical composition and anti-inflammatory activity of the essential oil from the leaves of Limnocitrus littoralis (Miq.) Swingle from Vietnam. Natural Product Research 35, 9, 1550-1554; https://doi.org/10.1080/14786419.2019.1652286

Sahu, A.R.; Sahu, M.; Raal, A. (2021). An ethnobotanical study on native plants of Bargarh District of Western Odisha, India in relieving urogenital ailments. Ethnobotany Research & Applications
21, 29, 1-11; http://www.ethnobotanyjournal.org/index.php/era/article/view/2591

Tung, N.T.; Hung, N.Q.; Luyen, N.T.; Dat, N.T.; Püssa, T.; LRusalepp, L; Ilisson, M.; Raal, A. (2021). Chemical constituents and biological activities of Balanophora fungosa varietas globosa growing in Vietnam, as well as comparative chromatography with some species of the genus Balanophora J. R. & G. Forst. Proceedings of the Estonian Academy of Sciences 70, 1, 40–50; https://doi.org/10.3176/proc.2021.1.01

Sotsiaalfarmaatsia & Kliiniline farmaatsia

Sepp, K.; Cavaco, A.M.; Raal, A.; Volmer, D. (2021). Profession driven improvement of the quality of pharmacy practice - Implementation of community pharmacy services Quality Guidelines in Estonia. Healthcare, 9, 804, 1-24; https://doi.org/10.3390/healthcare9070804

Sepp, K.; Volmer, D. (2021). Use of face-to-face assessment methods in e-learning - An example of an objective structured clinical examination (OSCE) test. Pharmacy, 9, 104, 1-9; https://doi.org/10.3390/pharmacy9030144

Tuula, A.; Volmer, D.; Jõhvik, L.; Rutkovska, I.; Treciokiene, I.; Merks, P.; Waszyk-Nowaczyk, M.; Drozd, M.; Tatarevic, A.; Radovanlija, M.; Pacadi, C.; Meštrovic, A.; Viola, R.; Soós, G.; Rais, C.; Táerel, A.-E.; Kuzelova, M.; Zare, M.; Peymani, P.; Oona, M.; Scott, M. (2021). Factors facilitating and hindering development of a medication use review service in Eastern Europe and Iran - Cross-sectional exploratory study. Healthcare, 9, 1207, 1-11; https://doi.org/10.3390/healthcare9091207

Teder, K.; Jõhvik, L.; Meos, A.; Saar, M.; Visbek, A.; Volmer, D.; Karjagin, J. (2021). Solid oral medications' suitability for use in enteral feeding tubes. Nursing Critical Care, 1-8; DOI: 10.1111/nicc.12729

Lubi, K.; Sepp, K.; Rass, H.; Roostar, K.; Volmer, D. (2021). A qualitative study of the challenges in rearranging community pharmacy service provision during the COVID-19 public health emergency: The prism of social practice theory. Public Health in Practice, 2, 1-7; https://doi.org/10.1016/j.puhip.2021.100212

Lubi, K.; Raal, A.; Taba, P. (2021). Ethnic identity in transition: the potential impact of ethnicityon chronic illness’ medication adherence in post-Soviet country. Journal of Racial and Ethnic Health Disparities 1-7; https://doi.org/10.1007/s40615-021-01048-x

Volmer, D.; Sepp, K.; Raal, A. (2021). Students’ feedback on the development of a competency-based pharmacy education (CBPE) at the University of Tartu, Estonia. Pharmacy 9, 45, 1-16; https://doi.org/10.3390/pharmacy9010045

Sepp, K.; Tuula, A.; Bobrova, V.; Volmer, D. (2021). Primary health care policy and vision for community pharmacy and pharmacists in Estonia. Pharmacy Practice 19, 2;  https://dx.doi.org/10.18549/pharmpract.2021.2.2404 
 

2020 Publikatsioonid

Farmatseutiline tehnoloogia, Nanotehnoloogia & Füüsikaline farmaatsia

Akhmetova, A.; Lanno, G.-M.; Kogermann, K.; Malmsten, M.; Rades, T.; Heinz, A. (2020). Highly elastic and water stable zein microfibers as a potential drug delivery system for wound healing.
Pharmaceutics 12, 458, 1-19; doi:10.3390/pharmaceutics12050458

Ramos, C.; Lanno, G.-M.; Laidmäe, I.; Meos, A.; Härmas, R.; Kogermann, K. (2020). High humidity electrospinning of porous fibers for tuning the release of drug delivery systems. International Journal of Polymeric Materials and Polymeric Biomaterials https://doi.org/10.1080/00914037.2020.1765361

Lanno, G.-M.; Ramos, C.; Preem, L.; Putrinš, M.; Laidmäe, I.; Tenson, T.; Korgermann, K. (2020). Antibacterial porous electrospun fibers as skin scaffolds for wound healing applications. ACS Omega 2020, 5, 46, 30011–30022; https://doi.org/10.1021/acsomega.0c04402

De Sio, L.; Ding, B.; Focsan, M.; Kogermann, K.; Pascoal-Faria, P.; Petronella, F.; Mitchell, G.; Zussman, E.; Pierini, F.  (2020). Personalized reusable face masks with smart nano‐assisted destruction of pathogens for COVID‐19: a visionary road. Chemistry – A European Journal 10.1002/chem.202004875; Link to VoR: https://doi.org/10.1002/chem.202004875

Partheniadis, I.; Nikolakakis, I.; Laidmäe, I.; Heinämäki, J. (2020). A Mini-Review: Needleless electrospinning of nanofibers for pharmaceutical and biomedical applications. MDPI Processes 8, 673, 1-20; doi:10.3390/pr8060673.

Farmakognoosia & Farmatseutiline bioloogia

Nguyen, Khan Viet; Ho, Duc Viet; Le, Nhan Trong; Phan, Kiem Van; Heinämäki, Jyrki; Raal, Ain; Nguyen, Hoai Thi (2020). Flavonoids and alkaloids from the rhizomes of Zephyranthes ajax Hort. and their cytotoxicity. Scientific Reports 10, 1-6 (22193); www.nature.com/scientificreports; https://doi.org/10.1038/s41598-020-78785-2

Raal, A.; Meos, A.; Hinrikus, T.; Heinämäki, J.; Romāne, E.; Gudienė, V.; Jakštas, V.; Koshovyi, O.; Kovaleva, A.; Fursenco, C.; Chiru, T.; Nguyen H.T. (2020). Dragendorff's reagent: Historical perspectives and current status of a versatile reagent introduced over 150 years ago at the University of Dorpat, Tartu, Estonia. Pharmazie 75, 299-306; doi: 10.1691/ph.2020.0438

Nguyen, Khan Viet; Ho, Duc Viet; Nguyen, Hien Minh; Do, Thao Thi; Phan, Kiem Van; Morita, Hiroyuki; Heinämäki, Jyrki; Raal, Ain; Nguyen, Hoai Thi (2020). Chiro-inositol derivatives from Chisocheton paniculatus showing inhibition of nitric oxide production. Journal of Natural Products, 83, 1201-1206. https://dx.doi.org/10.1021/acs.jnatprod.9b01239 

Kapp, Karmen; Orav, Anne; Roasto, Mati; Raal, Ain; Püssa, Tõnu; Vuorela, Heikki; Tammela, Päivi; Vuorela, Pia (2020).
Composition and Antibacterial Effect of Mint Flavorings in Candies and Food Supplements.
Planta Medica, 1−8.10.1055/a-1158-1699 [ilmumas].

Le, N.T.; Ho, D.V.; Doan, T.Q.; Le, A.T.; Raal, A.; Usai, D.; Sanna, G.; Carta, A.; Rappelli, P.; Diaz, N.; Cappuccinelli, P.; Zanetti, S.; Nguyen, H.T.; Donadu, M.G. (2020).
Biological activities of essential oils from leaves of paramignya trimera (Oliv.) guillaum and limnocitrus littoralis (miq.) swingle.
Antibiotics, 9 (4).10.3390/antibiotics9040207.

Le, NT; Ho, DV; Doan, TQ; Le, AT; Raal, A; Usai, D; Madeddu, S; Marchetti, M; Rapelli, P; Diaz, N; Zanetti, S; Nguyen TH; Capuccinelli P; Donadu, PC (2020).
In Vitro Antimicrobial Activity of Essential Oil Extracted from Leaves of Leoheo domatiophorus Chaowasku, D.T. Ngo and H.T. Le in Vietnam.
Plants, 9 (453), 1−14.10.3390/plants9040453.

Tran, Linh; Ho, Duc; Le, Dung; Nguyen, Hoai; Raal, Ain (2020).
The effect of Pogostemon auricularius fractions and its compounds on some proinflammatory and anti-inflammatory molecules in LPS-stimulated RAW 264.7 macrophages.
American Journal of Physiology, Biochemistry and Pharmacology, 10 (1), 1−7.10.5455/ajpbp.20190920041706.

Sotsiaalfarmaatsia & Kliiniline farmaatsia

Sepp, K.; Kukk, C.; Cavaco, A.; Volmer, D. (2020). How involvement of community pharmacies improves accessibility to and awareness about flu vaccination? – An example from Estonia. Expert Reviews of Vaccines 19, 10, 983-990. https://doi.org/10.1080/14760584.2020.1825949

Chiru, Tatiana; Fursenco, Cornelia; Ciobanu, Nicolae; Dinu, Mihaela; Popescu, Emanuela; Ancuceanu, Robert; Volmer, Daisy; Raal, Ain (2020).
Use of medicinal plants in complementary treatment of the common cold and influenza – perception of pharmacy customers in Moldova and Romania.
Journal of Herbal Medicine, 100346.10.1016/j.hermed.2020.100346 [ilmumas].

 

2019 Publikatsioonid

Farmatseutiline tehnoloogia, Nanotehnoloogia & Füüsikaline farmaatsia

Viet Nguyen, K.; Laidmäe, I.; Kogermann, K.; Lust, A.; Meos, A.; Viet Ho, D.; Raal, A.; Heinämäki, J.; Thi Nguyen, H. (2019).
Preformulation study of electrospun haemanthamine-loaded amphiphilic nanofibers intended for a solid template for self-assembled liposomes.
Pharmaceutics, 11 (10), 499.10.3390/pharmaceutics11100499.

Hakkarainen, E.; Kõrkjas, A.; Laidmäe, I.; Lust, A.; Semjonov, K.; Kogermann, K.; Nieminen, H.J.; Salmi, A.; Korhonen, O.; Haeggström, E.; Heinämäki, J. (2019).
Comparison of traditional and ultrasoundenhanced electrospinning in fabricating nanofibrous drug delivery systems.
Pharmaceutics, 11 (10), 495.10.3390/pharmaceutics11100495.

Preem, L.; Bock, F.; Hinnu, M.; Putrins, M.; Sagor, K.; Tenson, T.; Meos, A.; Ostergaard, J.; Kogermann, K. (2019).
Monitoring of antimicrobial drug chloramphenicol release from electrospun nano- and microfiber mats using UV imaging and bacterial bioreporters.
Pharmaceutics, 11 (9), ARTN 487.10.3390/pharmaceutics11090487.

Paaver, U.; Heinämäki, J.; Kassamakov, I.; Ylitalo, T.; Hæggström, E.; Laidmäe, I.; Kogermann, K. (2019).
Quasi-dynamic dissolution of electrospun polymeric nanofibers loaded with piroxicam.
Pharmaceutics, 11 (10), 491.10.3390/pharmaceutics11100491.

Viidik, L.; Seera, D.; Antikainen, O.; Kogermann, K.; Heinämäki, J.; Laidmäe, I. (2019).
3D-printability of aqueous poly(ethylene oxide) gels.
European Polymer Journal, 120 (109206), 1−10.10.1016/j.eurpolymj.2019.08.033.

Farmakognoosia & Farmatseutiline bioloogia

Doan Quoc Tuan; Ho Viet Duc; Le Trong Nhan; Le Tuan Anh; Nguyen Thi Hoai; Raal, Ain (2019).
Constituents of Essential Oils from the Leaves of Paramignya trimera (Oliv.) Guillaum from Vietnam.
Journal of Essential Oil Bearing Plants, 22 (2), 391−395.10.1080/0972060X.2019.1582362.

Doan, Thi Huong; Ho, Viet Duc; Le, Thi Bich Hien; Le, Tuan Anh; Pham, Thanh Ky; Nguyen, Thi Hoai; Raal, Ain (2019).
Two new abietane diterpenes huperphlegmarins A and B from Huperzia phlegmaria.
Natural Product Research, 33 (14), 2051−2059.10.1080/14786419.2018.1484462.

Duc Viet Ho; Hanh Nhu Thi Hoang; Hung Quoc Vo; Hien Minh Nguyen; Raal, Ain; Hoai Thi Nguyen (2019).
A new triterpene ester and other chemical constituents from the aerial parts of Anodendron paniculatum and their cytotoxic activity (vol 20, pg 188, 2017).
Journal of Asian Natural Products Research, 21 (7), 725−725.10.1080/10286020.2017.1359394.

Ho, Duc Viet; Tran, Linh Thuy Thi; Le, Dung Viet; Tran, Hung Manh; Le, Nhan Trong; Le, Anh Tuan; Nguyen, Hoai Thi; Raal, Ain (2019).
A new triterpene and a new phloroglucinol derivative from the aerial parts of Pogostemon auricularius.
Chemistry of Natural Compounds, 55 (5), 890−894.10.1007/s10600-019-02839-9.

Nguyen, Hoai Thi; Tran, Linh Thuy Thi; Ho, Duc Viet; Phan, Kiem Van; Raal, Ain; Morita, Hiroyuki (2019).
Three new inositol derivatives from Chisocheton paniculatus.
Tetrahedron Letters, 60 (28), 1841−1844.10.1016/j.tetlet.2019.06.015.

Tran, Linh Thuy Thi; Ho, Duc Viet; Le, Dung Viet; Van Phan, Kiem; Nguyen, Hoai Thi; Raal, Ain (2019).
Apoptosis-Inducing Effect of Pogostemin A Isolated from the Aerial Parts of Pogostemon auricularius Against the Human Lung Cancer Cells.
Journal of Biologically Active Products From Nature, 9 (5), 320−327.10.1080/22311866.2019.1687334.

Sotsiaalfarmaatsia & Kliiniline farmaatsia

Bobrova V.; Heinämäki J.; Honkanen O.; Desselle S.; Airaksinen M.; Volmer D. (2019).
Older adults using multi-dose dispensing exposed to risks of potentially inappropriate medications.
Research in Social and Administrative Pharmacy, 15, 1102−1106.10.1016/j.sapharm.2018.11.007.

Volmer, D.; Sepp, K.; Raal, A.; Atkinson, J. (2019).
Pharmacy Practice and Education in Estonia.
Pharmacy, 7 (3).10.3390/pharmacy7030087.

 

2018 Publikatsioonid

Farmatseutiline tehnoloogia, Nanotehnoloogia & Füüsikaline farmaatsia

Nieminen, H.J.; Laidmäe, I.; Salmi, A.; Rauhala, T.; Paulin, T.; Heinämäki, J.; Haeggström, E. (2018).
Ultrasound-enhanced electrospinning.
Scientific Reports, 8 (4437), 1−6.10.1038/s41598-018-22124-z.

Kogermann, K.; Lass, J.; Nellis, G.; Metsvaht, T.; Lutsar, I. (2018).
Age-appropriate formulations including pharmaceutical excipients in neonatal medicines.
Current Pharmaceutical Design, 23, 5779−5789.10.2174/1381612823666170926122613.

Zupančič, Š.; Preem, L.; Kristl, J.; Putrinš, M.; Tenson, T.; Kocbek, P.; Kogermann, K. (2018).
Impact of PCL nanofiber mat structural properties on hydrophilic drug release and antibacterial activity on periodontal pathogens.
European Journal of Pharmaceutical Sciences, 122, 347−358.10.1016/j.ejps.2018.07.024.

Semjonov, K.; Lust, A.; Kogermann, K.; Laidmäe, I.; Maunu, S.L.; Hirvonen, S.-P., Yliruusi, J.; Nurk, G.; Lust, E.; Heinämäki, J. (2018).
Melt-electrospinning as a method to improve the dissolution and physical stability of a poorly water-soluble drug.
European Journal of Pharmaceutical Sciences, 121, 260−268.10.1016/j.ejps.2018.06.004.

Semjonov, K.; Salm, M.; Lipiäinen, T.; Kogermann, K.; Lust, A.; Laidmäe, I.; Antikainen, O.; Strachan, C.J.; Ehlers, H.; Yliruusi, J.; Heinämäki, J. (2018).
Interdependence of particle properties and bulk powder behavior of indomethacin in quench-cooled molten two-phase solid dispersions.
International Journal of Pharmaceutics, 541 (1-2), 188−197.10.1016/j.ijpharm.2018.02.039.

Laidmae, I.; Erglis, K.; Cebers, A.; Janmey, P.A.; Uibo, R. (2018).
Salmon fibrinogen and chitosan scaffold for tissue engineering: in vitro and in vivo evaluation.
Journal of Materials Science: Materials in Medicine, 29 (12), ARTN 182.10.1007/s10856-018-6192-8.

Farmakognoosia & Farmatseutiline bioloogia

Linh Thuy Thi Tran; Duc Viet Ho; Dung Viet Le; Tran Manh Hung; Hoai Thi Nguyen; Raal, Ain (2018).
Three new phloroglucinol derivatives from the aerial parts of Pogostemon auricularius and their cytotoxic activity.
Phytochemistry Letters, 28, 88−92.10.1016/j.phytol.2018.09.016.

Nguyen T.H.; Ho V.D.; Raal A.; Morita H. (2018).
A new limonoid from Chisocheton paniculatus fruit collected in Vietnam and its NO production inhibitory activity.
Natural Product Communications, 13 (11), 1255−1257.10.1080/14786419.2018.1428600.

Nguyen, H.T.; Ho, D.V.; Nguyen P.D.Q.; Vo, H.Q.; Do, T.T.; Raal, Ain (2018).
Cytotoxic evaluation of compunds isolated from the aerial parts of Hedyotis pilulifera and methanol extract of Inonotus obliquus.
Natural Product Communications, 13 (8), 939−941.10.1177/1934578X1801300805.


Nguyen, Hoai Thi; Doan, Huong Thi; Ho, Duc Viet; Pham, Ky Thanh; Raal, Ain; Morita, Hiroyuki (2018).
Huperphlegmines A and B, two novel Lycopodium alkaloids with an unprecedented skeleton from Huperzia phlegmaria, and their acetylcholinesterase inhibitory activities.
Fitoterapia, 129, 267−271.10.1016/j.fitote.2018.07.016.

Nguyen, Hoai Thi; Tran, Linh Thuy Thi; Ho, Duc Viet; Le, Dung Viet; Raal, Ain; Morita, Hiroyuki (2018).
Pogostemins A-C, three new cytotoxic meroterpenoids from Pogostemon auricularius.
Fitoterapia, 130, 100−104.10.1016/j.fitote.2018.08.015.

Raal, A.; Relve, P.; Kõivupuu, M. (2018).
Modern beliefs regarding medicinal plants in Estonia.
Journal of Baltic Studies, 49 (3), 387−403.10.1080/01629778.2018.1453851.

Sotsiaalfarmaatsia & Kliiniline farmaatsia

Laius, O.; Pisarev ,H.; Volmer, D.; Kõks, S., Märtson, A., Maasalu, K. (2018).
Use of a national database as a tool to identify primary medication non-adherence: The Estonian ePrescription system.
Research in Social and Administrative Pharmacy, 14 (8), 776−783.10.1016/j.sapharm. 2017.10.003.

 

2017 Publikatsioonid

Farmatseutiline tehnoloogia, Nanotehnoloogia & Füüsikaline farmaatsia

Palo, M.; Kogermann, K.; Laidmäe, I.; Meos, A.; Preis, M.; Heinämäki, J.; Sandler, N. (2017).
Development of oromucosal dosage forms by combining electrospinning and inkjet printing.
Molecular Pharmaceutics, 14 (3), 802−820.10.1021/acs.molpharmaceut.6b01054.

Heinämäki, J.; Pirttimaa, M.M.; Alakurtti, S.; Pitkänen, H.P.; Kanerva, H.; Hulkko, J.; Paaver, U.; Aruväli, J.; Yliruusi, J.; Kogermann, K. (2017).
Suberin fatty acids from outer birch bark: Isolation and physical material characterization.
Journal of Natural Products, 80, 916−924.10.1021/acs.jnatprod.6b00771.

Hautala, J.; Kääriäinen, T.; Hoppu, P.; Kemell, M.; Heinämäki, J.; Cameron, D.; George, S.; Juppo A.M. (2017).
Atomic layer deposition—A novel method for the ultrathin coating of minitablets. International
Journal of Pharmaceutics, 531, 47−58.10.1016/j.ijpharm.2017.08.010.

Preem, L.; Mahmoudzadeh, M.; Putrinš, M.; Meos, A.; Laidmäe, I.; Romann, T.; Aruväli, J.; Härmas, R.; Koivuniemi, A.; Bunker, A.; Tenson, T.; Kogermann, K. (2017).
Interactions between chloramphenicol, carrier polymers, and bacteria-implications for designing electrospun drug delivery systems countering wound infection.
Molecular Pharmaceutics, 14 (12), 4417−4430.10.1021/acs.molpharmaceut.7b00524.

Ho, H.N.; Laidmäe, I.; Kogermann, K.; Lust, A.; Meos, A.; Nguyen, C.N.; Heinämäki, J. (2017).
Development of electrosprayed artesunate-loaded core–shell nanoparticles.
Drug Development and Industrial Pharmacy, 43 (7), 1134−1142.10.1080/03639045.2017.1300163.

Semjonov, K.; Kogermann, K.; Laidmäe, I.; Antikainen, O.; Strachan, C.J.; Ehlers, H.; Yliruusi, J.; Heinämäki, J. (2017).
The formation and physical stability of two-phase solid dispersion systems of indomethacin in supercooled molten mixtures with different matrix formers.
European Journal of Pharmaceutical Sciences, 97, 237−246.10.1016/j.ejps.2016.11.

Farmakognoosia & Farmatseutiline bioloogia

Meos, Andres; Saks, Liis; Raal, Ain (2017).
Content of alkaloids in ornamental Papaver somniferum L. cultivars growing in Estonia.
Proceedings of the Estonian Academy of Sciences, 1, 34−39.10.3176/proc.2017.1.04.

Ho, Viet Duc; Hoang, Thi Nhu Hanh; Vo, Quoc Hung; Phan, Van Kiem; Le, Tuan Anh; Pham, Viet Ty; Nguyen, Minh Hien; Kodama, Takeshi; Ito, Takuya; Morita, Hiroyuki; Raal, Ain; Nguyen, Thi Hoai (2017).
Cycloartane-type triterpene glycosides anopanins A-C with monoacyl-digalactosylglycerols from Anodendron paniculatum.
Phytochemistry, 144, 113−118.10.1016/ j.phytochem.2017.09.004.

Nguyen, Hoai Thi; Ho, Duc Viet; Vo, Hung Quoc; Le, Anh Tuan; Nguyen, Hien Minh; Kodama, Takeshi; Ito, Takuya; Morita, Hiroyuki; Raal, Ain (2017).
Antibacterial activities of chemical constituents from the aerial parts of Hedyotis pilulifera.
Pharmaceutical biology, 55 (1), 787−791.10.1080/13880209.2017.1279673.

Rusalepp, Linda; Raal, Ain; Püssa, Tõnu; Mäeorg, Uno (2017).
Comparison of chemical composition of Hypericum perforatum and H. maculatum in Estonia.
Biochemical Systematics and Ecology, 73, 41−46.10.1016/j.bse.2017.06.004.


Nguyen, Thi Hoai; Ho, Viet Duc; Vo, Quoc Hung; Hoang, Xuan Huyen Trang; Kodoma, Takeshi; Ito, Takuya; Morita, Hiroyuki; Raal, Ain (2017).
The components from aerial parts of Sarcosperma affinis Gagnep. and their antibacterial activities.
Cogent Chemistry, 2, 1−8.10.1080/23312009.2016.1254421.


Meos, Andres; Zaharova, Irina; Kask, Marten; Raal, Ain (2017).
Content of ascorbic acid in common cowslip (Primula veris L.) compared to common food plants and orange juices.
Acta Biologica Cracoviensia Series Botanica, 59 (1), 1−14.10.1515/abcsb-2016-0020.


Sak, Katrin; Nguyen, Thi Hoai; Ho, VViet Duc; Do, Thi Thao; Raal, Ain (2017).
Cytotoxic effect of chamomile (Matricaria recutita) and marigold (Calendula officinalis) extract on human melanoma SKMEL-2 and epidermoid carcinoma KB cells.
Cogent Medicine, 4. 


Sotsiaalfarmaatsia & Kliiniline farmaatsia

Volmer, D.; Sepp, K.; Veski, P.; Raal, A. (2017).
The Implementation of Pharmacy Competence Teaching in Estonia.
Pharmacy, 5 (2), 1−16.10.3390/pharmacy5020018.

Cavaco, A.; Schaafsma, E.; Bicer, B.K.; Sahne, B.S.; Volmer, D.; Ozcelikay, G.; Kurlovic, J.; Krauja, N.; Postma, M.; Yegenoglu, S. (2017).
Internet and computer use amongst European pharmacy undergraduates: Exploring similarities and differences.
Farmacia, 65 (3), 407−413.

Volmer, D.; Sepp, K.; Veski, P.; Raal, A. (2017).
The implementation of pharmacy competence teaching in Estonia.
Pharmacy, 5 (2), 1.10.3390/pharmacy5020018.
 

2016 Publikatsioonid

Farmatseutiline tehnoloogia, Nanotehnoloogia & Füüsikaline farmaatsia

Penkina, A.; Semjonov, K.; Hakola, M.; Vuorinen, S.; Repo, T.; Yliruusi, J.; Aruväli, J.; Kogermann, K.; Veski, P.; Heinämäki, J. (2016).
Towards improved solubility of poorly water-soluble drugs: cryogenic cogrinding of piroxicam with carrier polymers.
Drug Development and Industrial Pharmacy, 42 (3), 378−388.10.3109/03639045.2015.1054400.

Tamm, I.; Heinämäki, J.; Laidmäe, I.; Rammo, L.; Paaver, U.; Ingebrigtsen, S.G.; Škalko-Basnet, N.; Halenius, A.; Yliruusi, J.; Pitkänen, P.; Alakurtti, S.; Kogermann, K. (2016).
Development of suberin fatty acids and chloramphenicol-loaded antimicrobial electrospun nanofibrous mats intended for wound therapy.
Journal of Pharmaceutical Sciences, 1−9.10.1016/j.xphs.2015.12.025.

Hautala, J.; Heinämäki, J.; Hietala, S.; Juppo A.M. (2016).
Development of novel flavored Eudragit® E films for feline minitablet coatings.
Journal of Drug Delivery Science and Technology, 34, 41−50.10.1016/j.jddst.2016.03.003.

Paaver, U.; Laidmäe, I.; Santos, H.A.; Yliruusi, J.; Aruväli, J.; Kogermann, K.; Heinämäki, J. (2016).
Development of a novel electrospun nanofibrous delivery system for poorly water-soluble β-sitosterol. Asian
Journal of Pharmaceutical Sciences, 11 (4), 500−506.10.1016/j.ajps.2016.04.005.

Palo, M.; Kogermann, K.; Genina, N.; Fors, D.; Peltonen, J.; Heinämäki, J.; Sandler, N. (2016).
Quantification of caffeine and loperamide in printed formulations by infrared spectroscopy.
Journal of Drug Delivery Science and Technology, 34, 60−70.10.1016/j.jddst.2016.02.007.

Kogermann, K.; Putrinš, M.; Tenson, T. (2016).
Single-cell level methods for studying the effect of antibiotics on bacteria during infection.
European Journal of Pharmaceutical Sciences, 95, 2−16.10.1016/j.ejps.2016.08.042.

Farmakognoosia & Farmatseutiline bioloogia

Volmer, D.; Raal, A.; Kalle, R.; Sõukand, R. (2016).
The use of Panax ginseng and its analogues among pharmacy customers in Estonia: a cross-sectional study.
Acta Poloniae Pharmaceutica Drug Research, 73 (3), 795−802.

Raal, A.; Orav, A.; Nesterovitsch, J.; Maidla, K. (2016).
Analysis of carotenoids, flavonoids and essential oil of Calendula officinalis Cultivars growing in Estonia.
Natural Product Communications, 8, 1157−1160.

Raal, A.; Orav, A.; Gretchushnikova, T. (2016).
beta-Asarone content and essential oil composition of Acorus calamus L. rhizomes from Estonia.
Journal of Essential Oil Research, 4, 299−304.10.1080/10412905.2016.1147391.

Sotsiaalfarmaatsia & Kliiniline farmaatsia

Atkinson, J.; De Paepe, K.; Sánchez Pozo, A.; Rekkas D.; Volmer, D.; Hirvonen, J.; Bozic, B.; Skowron, A.; Mircioiu, C.; Marcincal, A.; Koster, A.; Wilson, K.; van Schravendijk, C. (2016).
A study on how industrial pharmacists rank competences for pharmacy practice: A case for industrial pharmacy specialization.
Pharmacy, 13 (4(1)), 1−15.10.3390/pharmacy4010013.

Atkinson, J.; De Paepe, K.; Sánchez Pozo, A.; Rekkas, D.; Volmer, D.; Hirvonen, J.; Bozic, B.; Skowron, A.; Mircioiu, C.; Marcincal, A.; Koster, A.; Wilson, K.; van Schravendijk, C.; Hocevar, S. (2016).
How do European pharmacy students rank competences for practice?
Pharmacy, 4 (8), 2−16.10.3390/pharmacy4010008.

Atkinson, J.; De Paepe, K.; Sánchez Pozo, A.; Rekkas, D.; Volmer, D.; Hirvonen, J.; Bozic, B.; Skowron, A.; Mircioiu, C.; Marcincal, A.; Koster, A.; Wilson, K.; van Schravendijk, C.; Wilkinson, J. (2016).
What is a pharmacist: Opinions of pharmacy department academics and community pharmacists on competences required for pharmacy practice.
Pharmacy, 12 (4), 2−12.10.3390/pharmacy4010012.

Atkinson, J.; De Paepe, K.; Sánchez Pozo, A.; Rekkas, D.; Volmer, D.; Hirvonen, J.; Bozic, B.; Skowron, A.; Mircioiu, C.; Marcincal, A.; Koster, A.; Wilson, K.; van Schravendijk, C. (2016).
The second round of the PHAR-QA survey of competences for pharmacy practice.
Pharmacy, 4 (27), 2−19.10.3390/pharmacy4030027.

Atkinson, J.; Sánchez Pozo, A.; Rekkas, D.; Volmer, D.; Hirvonen, J.; Bozic, B.; Skowron, A.; Mircioiu, C.; Sandulovici, R.; Marcincal, A.; Köster, A.; Wilson, K.; van Schravendijk, C.; Frontini, R.; Price, R.; Bates, I.; De Paepe, K. (2016).
Hospital and community pharmacists’ perceptions of which competences are important for their practice.
Pharmacy, 4(2) (21), 2−18.10.3390/ pharmacy4020021.

Gross, M.; Volmer, D. (2016).
Restrictions to pharmacy ownership and vertical integration in Estonia - Perception of different stakeholders.
Pharmacy, 4 (18), 1−9.doi:10.3390/pharmacy 4020018.

Volmer, D.; Raal, A.; Kalle, R.; Sõukand, R. (2016).
The use of Panax ginseng and its analogues among pharmacy customers in Estonia: a cross-sectional study.
Acta Poloniae Pharmaceutica Drug Research, 73 (3), 795−802.

Volmer, D.; Sokirskaja, A.; Laaksonen, R.; Vainio, K.; Sandler, N.; Halvorsen, K.H.; Kjome, R.L.S.; Gizurarson, S.; Muceniece, R.; Maurina, B.; Dauksiene, J.; Ruuben, L.; Björnsdottir, I.; Ratassepp, T.; Heinämäki, J. (2016).
Perception of the professional knowledge of and education on the medical technology products among the pharmacists in the Baltic and Nordic countries - A Cross-sectional exploratory study.
Pharmacy, 4 (29), 2−9.10.3390/pharmacy4040029.
 

2015 Publikatsioonid

Farmatseutiline tehnoloogia, Nanotehnoloogia & Füüsikaline farmaatsia

Heinämäki, J.; Halenius, A.; Paavo, M.; Alakurtti, S.; Pitkänen, P.; Pirttimaa, M.; Paaver, U.; Kirsimäe, K.; Kogermann, K.; Yliruusi, J. (2015).
Suberin fatty acids isolated from outer birch bark improve moisture barrier properties of cellulose ether films intended for tablet coatings.
International Journal of Pharmaceutics, 489 (1-2), 91−99.10.1016/j.ijpharm.2015.04.066.

Lust, A.; Strachan, C.J.; Veski, P.; Aaltonen, J.; Heinämäki, J.; Yliruusi, J.; Kogermann, K. (2015).
Amorphous solid dispersions of piroxicam and Soluplus®: Qualitative and quantitative analysis of piroxicam recrystallization during storage.
International Journal of Pharmaceutics, 486, 306−314.10.1016/j.ijpharm.2015.03.079.

Paaver, U.; Heinämäki, J.; Laidmäe, I.; Lust, A.; Kozlova, J.; Sillaste, E.; Kirsimäe, K.; Veski, P.; Kogermann, K. (2015).
Electrospun nanofibers as a potential controlled-release solid dispersion system for poorly water-soluble drugs.
International Journal of Pharmaceutics, 479 (1), 252−260.10.1016/j.ijpharm.2014.12.024.

Putrinš, M.; Kogermann, K.; Lukk, E.; Lippus, M.; Varik, V.; Tenson, T. (2015).
Phenotypic heterogeneity enables uropathogenic Escherichia coli to evade killing by antibiotics and serum complement.
Infection and immunity, 83 (3), 1056−1067.10.1128/IAI.02725-14.

Farmakognoosia & Farmatseutiline bioloogia

Hoai, Nguyen Thi; Duc, Ho Viet; Thao, Do Thi; Orav, Anne; Raal, Ain (2015).
Selectivity of Pinus sylvestris extract and essential oil to estrogen-insensitive breast cancer cells Pinus sylvestris against cancer cells.
Pharmacognosy Magazine, 11(44) (Suppl 2), S290−S295.10.4103/0973-1296.166052.

Kondratas, R.; Gudienė, V.; Šimaitiene, Z.; Maurina, B.; Paju, K.; Hinrikus, T.; Raal, A. (2015).
The national pharmacopoeias of the Baltic States.
Pharmazie, 70 (10), 684−689.10.1691/ ph.2015.5082.

Nguyen, T.H.; Ho, V.D.; Do, T.T.; Bui, H.T.; Phan, V.K.; Sak, K.; Raal, A. (2015).
A new lignan glycoside from the aerial parts and cytotoxic investigation of Uvaria rufa.
Natural Product Research, 29 (3), 247−252.

Raal, Ain; Boikova, Tatjana; Püssa, Tõnu (2015).
Content and Dynamics of Polyphenols in Betula spp. Leaves Naturally Growing in Estonia.
Records of Natural Products, 9 (1, 9(1)), 41−48.


Sotsiaalfarmaatsia & Kliiniline farmaatsia

Volmer, D.; Ratassepp, T.; Shagandina, A.; Turunen, J.; Ahonen, R.; Heinämäki, J. (2015).
The role of community pharmacies in counseling of personal medical devices and drug-delivery products in Estonia.
Expert Review of Medical Devices, 12 (4), 487−493.10.1586/17434440.2015.1052405.

Ratassepp, T.; Shagandina, A.; Turunen, J.; Ahonen, R.; Veski, P.; Heinämäki, J.; Volmer, D. (2015).
Counseling on the use of personal medical devices and drug-delivery products – A traditional or extended community pharmacy service?
Farmacia, 63 (3), 388−393.

Gavronski, M.; Volmer, D.; Hartikainen, S.; Zharkovsky, A. (2015).
Potential drug interactions with statins: Estonian register-based study.
Open Medicine, 10 (1), 254−260.10.1515/med-2015-0038.

Atkinson, J.; De Paepe, K.; Sánchez Pozo, A.; Rekkas, D.; Volmer, D.; Hirvonen, J.; Bozic, B.; Skowron, A.; Mircioiu, C.; Marcincal, A.; Koster, A.; Wilson, K.; van Schravendijk, C.; Wilkinson, J. (2015).
Does the subject content of the pharmacy degree course influence the community pharmacist’s views on competencies for practice?
Pharmacy, 3, 137−153.10.3390/pharmacy 3030137.

Atkinson, J.; De Paepe, K.; Sánchez Pozo, A.; Rekkas, D.; Volmer, D.; Hirvonen, J.; Bozic, B.; Skowron, A.; Mircioiu, C.; Marcincal, A.; Koster, A.; Wilson, K.; van Schravendijk, C.; Wilkinson, J. (2015).
The PHARQA project: Competency framework for pharmacy practice - first steps, the results of the European network Delphi round 1.
Pharmacy, 3, 307−329.10.3390/pharmacy 3040307.

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