Research work at the Institute of Pharmacy is multidisciplinary and involves the following research areas:
Pharmaceutical chemistry research work is currently related with all other research areas.
PRG1903, Professor J. Heinämäki, University of Tartu, Faculty of Medicine, Institute of Pharmacy (coordinator).
The project aims to develop and test novel biomimetic composite of nanofibrous and three-dimensional (3D) bioprinted bone tissue constructs intended for use in bone regeneration and tissue modeling for studying disease and testing drugs.
To design such constructs, we will investigate how structural features and functions of native bone tissue can be mimicked in engineered constructs using novel biomaterial that has osteopromotive, angiogenic and antibacterial properties combined at the nanostructure. We will also develop our patented ultrasound-enhanced electrospinning method to suit the production of the biomimetic nanofibers (NFs) needed for this project. We will investigate cellular responses to mechanical microenvironments created by the NF-3D bioprinted biomimetic composites to better define the properties of engineered bone construct.
Knowledge obtained from the present research activities will be exploited for designing new regenerative and modeling of bone tissue.
Development of biorelevant assays for the analyses of multifunctional antimicrobial wound dressings for the treatment of wound infections (01.01.2022–31.12.2026)
Principal Investigator: Karin Kogermann; University of Tartu, Faculty of Medicine, Institute of Pharmacy